pcr detection of herpes simplex virus in human placenta and aborted materials in patients with spontaneous abortion
نویسندگان
چکیده
objective herpes simplex virus (hsv) infection during pregnancy may lead to fetal loss. the aim of this study was to explore the infection rate of hsv type 1 and 2 infection associated with spontaneous abortion in a pilot case-control study in two cities of iran in 2010. patients and methods placenta and curettage samples from 35 healthy full term neonates and 35 cases of spontaneous abortion with related questionnaires were collected. sample dna was extracted using qiagen extraction kit, and then pcr was applied for detection of both types of viruses. in parallel, results were checked using sinaclon detection kit. results in this study 2.8% (1/35) of samples taken from aborted materials were found to be hsv positive (p=0.497). differences were detected between case and control groups regarding vaginal infection (p =0.001) and having previous spontaneous abortion (p =0.018). conclusion our findings revealed that hsv can be an abortion-related factor in pregnancy.
منابع مشابه
Detection of Herpes Simplex Virus Infection in Cerebrospinal Fluid
ABSTRACT Background and Objective: Herpes simplex encephalitis is a life-threatening consequence of the central nervous system (CNS) infection with Herpes simplex virus (HSV). Although it is a rare disease, mortality rates reach 70% in the absence of therapy and only a minority of individuals can return to normal function. The aim of this study was to d...
متن کاملFrequency of Herpes simplex virus in patients with Stroke by PCR
Herpes simplex virus (HSV) causes a wide range of pathologies in the human central nervous system (CNS) such as stroke. It was proposed that there is an association between HSV infection and stroke with different results reported by the researchers using different methods. This study aimed to investigate the frequency of HSV among stroke patient and control groups. We detected HSV in 28 stroke ...
متن کاملDetection of Herpes Simplex Virus DNA in Pseudoexfoliation Syndrome
Background: Pseudoexfoliation syndrome is one of the most common identifiable causes of open angle glaucoma. It has unknown etiology and pathogenesis. Infection, possibly viral, is one of the proposed pathogenic mechanisms in this condition. In the present study the presence of herpes simplex virus (HSV) in specimens of anterior lens capsule of patients with pseudoexfoliation syndrome has been ...
متن کاملInvestigation of Frequency of Herpes Simplex Virus in Patients with Type 2 Diabetes and Healthy Individuals by PCR and ELISA
ABSTRACT Background and Objectives: Previous studies have demonstrated the relationship between viral infections and risk of developing type 1 diabetes. The aim of this study was to investigate the frequency of Herpes simplex virus (HSV) in patients with type 2 diabetes and healthy control individuals using PCR and ELISA. &n...
متن کاملAnalysis of Herpes Simplex Virus in Suspected Encephalitis, Keratitis and Dermal Infections Using Real- Time PCR
Background & Objectives: Herpes viruses can cause diseases in the clinical range. The virus can cause infection in various body parts, especially eyes and nervous system. The aim of this study was at evaluating the Real-Time TaqMan probe PCR in diagnosing and monitoring of the patients with suspected HSV infections.Materials & Methods: More than a thousand patients with suspected HSV infection...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
archives of clinical infectious diseasesجلد ۶، شماره supl، صفحات ۱۷-۲۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023